Phonophoresis or sonophoresis is consists of use of ultrasonic energy for enhancement of drugs through the transdermal or topical route. Some 40 years ago, the combination of ultrasound and steroids or analgesics has been utilized by physiotherapist to treat a several range of muscular and arthritic conditions. But this method involves several subjective and non-quantitative basis including the common deficiencies of proper control along with incomplete accounts of dosimetry and regarding the protocols too. The non-calibrated ultrasound source is also vital deficiency of this method but fortunately several researches has also been done for improvement regarding these deficiencies. Hence, it shows some potential application in the field of drug delivery beneficial than the conventional techniques.
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